RECOMBINANT AAV BATCH PROFILING BY NANOPORE SEQUENCING ELUCIDATES PRODUCT-RELATED DNA IMPURITIES AND VECTOR GENOME LENGTH DISTRIBUTION

Recombinant AAV batch profiling by nanopore sequencing elucidates product-related DNA impurities and vector genome length distribution

During production, recombinant adeno-associated virus (rAAV) capsids are equipped with heterogeneous genetic payloads including undesired DNA impurities as well as truncated vector Knife Storage genomes.Comprehensive analysis of encapsidated DNA by long-read next-generation sequencing is destined to guide platform optimization and provide crucial i

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Theoretical and practical aspects regarding the role of the working model in the workflow of porcelain fused to metal fixed restorations - Preliminary study

In dental practice, the fidelity of a model is given by the quality and type of material used, the technique by which it is made, and last but not least by the experience and skill of the dental technician.But, the Knife Storage emergence of CAD-CAM technology has led to a major change in the stages of making the working model, through the developm

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Computer hardware for radiologists: Part 2

Computers are an integral part of modern radiology equipment.In the first half of this two-part article, we dwelt upon some fundamental concepts regarding computer hardware, covering components like motherboard, central processing unit (CPU), chipset, random access memory (RAM), and memory modules.In this article, we describe the remaining computer

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Two-Dimensional Multi-Ring Dielectric Lens Antenna to Radiate Fan-Shaped Multi-Beams With Optimum Adjacent-Beam Overlapping Crossover by Genetic Algorithm

A two-dimensional (2-D) discrete dielectric lens antenna is designed to radiate fan-shaped multi-beam patterns for gain stability in beam switching.The target is to minimize adjacent-beam overlapping transition Keto regions and provide sufficient and similar gains for all field angles when the antenna is employed in a mobile device.This design star

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